Mastering Omnipod 5 Settings
In the second episode of the Omnipod 5 series on the Juicebox Podcast, Cari Berget, MPH, RN, CDE and host Scott Benner break down everything you need to know about setting up your Omnipod 5. Whether you're new to automated insulin delivery or transitioning from a manual pump or MDI, this episode is packed with insights that can help you optimize your system and improve your blood sugar control.
If you haven’t listened to our Omnipod 5 Pro Tip Overview (part one) or are curious about connectivity in part three, make sure to check those out as well—each episode builds on the last for a complete picture of how to get the most from your device.
Basal Settings & Their Role
Program Basal Rates Carefully:
When setting up your Omnipod Five, you must enter basal rates—even though these rates aren’t used during automated mode. They provide the initial estimation for your total daily insulin (TDI), ideally reflecting 40–50% of your total insulin needs. These numbers are critical because they serve as your fallback settings if you ever switch to manual mode.Dual Purpose of Basal Settings:
In automated mode, the system learns your adaptive basal rate based on the insulin it actually delivers over time. When you change pods, the new pod updates its baseline using data from the previous pod. This makes getting your initial settings right essential for faster, more accurate system learning.Consult Your Healthcare Provider:
Never just “make up” numbers—work with your doctor or diabetes educator to determine your starting basal rates, as these will be the settings you rely on if you ever need to revert to manual mode.
Bolusing, Carb Ratios & Correction Factors
Accurate Bolusing is Critical:
To support the system’s learning and to prevent post-meal highs, bolus 10–15 minutes before eating. Use the Bolus calculator consistently; it factors in your insulin-to-carb ratio, correction factor, and any insulin on board to recommend the proper dose.Adjusting Carb Ratios:
Transitioning to an automated system may mean you need stronger carb ratios. Since the adaptive basal algorithm sometimes suspends insulin before a meal, you might require more insulin during mealtime boluses than you did with a manual pump or MDI. Monitor your post-meal blood sugars over a few weeks and consult your healthcare provider for adjustments if needed.Keep Your Correction Factor Updated:
Your correction (or insulin sensitivity) factor must reflect your current insulin needs. Outdated values may lead to underdosing when you need a correction dose, so review these settings with your provider regularly.Understanding “Correct Above”:
The “correct above” setting determines the threshold at which a correction bolus is triggered. For example, if set at 140 mg/dL, any reading above that will prompt a calculation for additional insulin. Ensure this aligns with your treatment goals.
Target Glucose Settings & Reverse Correction
Set Your Target Thoughtfully:
Omnipod Five allows you to adjust your target between 110 and 150 mg/dL in 10-mg/dL increments. A lower target (e.g., 110) encourages more aggressive insulin delivery, while a higher target reduces the insulin dose. Remember, this setting is used both by the adaptive basal algorithm and the Bolus calculator.Use Reverse Correction with Caution:
Reverse correction aims to reduce insulin delivery if your glucose falls below your target. In automated mode, it’s generally best to turn this off since the adaptive basal already works to prevent lows. It may have its place in manual mode, but most users will benefit from disabling it to avoid conflicts with bolus dosing.
Duration of Insulin Action (DIA)
Understand DIA’s Role:
The duration of insulin action (DIA) typically ranges from 3–4 hours and applies only to bolus calculations—not to the adaptive basal algorithm. Adjust DIA only in consultation with your healthcare provider if you notice that your correction bolus recommendations don’t align with your actual insulin action.
Extended Bolus Considerations
Extended Bolus Limitations in Automation:
Extended bolus options are available only in manual mode. For meals like pizza or Chinese food that digest slowly, the adaptive basal may already mimic an extended bolus response as it increases insulin delivery in response to rising glucose. Experiment with splitting your bolus—delivering part upfront and part later—if necessary, but always start by testing a single bolus dose.
Using Data & Adjusting Settings Over Time
Data-Driven Adjustments:
The Omnipod Five system continuously updates its understanding of your TDI with each pod change. Use the CGM graph on your controller to monitor trends, including time-in-range, glycemic variability, and post-meal highs. This data helps you know when to consult your healthcare provider for further adjustments.Keep a Record of Your Settings:
Document your initial settings and any subsequent changes. Tools like the Gluco data management system can simplify tracking your insulin delivery and glucose control, ensuring you have a reference if you need to reset or adjust your system.
General Philosophy & Tips for Success
Embrace the New Paradigm:
Automated insulin delivery is a shift from traditional manual pumping. Be open to a period of adjustment as you learn how the system’s adaptive basal algorithm works alongside your user-directed boluses.Patience and Iteration:
Give the system a few weeks (typically three to four pods) to fully adapt. Every data point is feedback—if something isn’t working, adjust gradually rather than seeing it as a setback.Prioritize Stability:
The goal is a stable glycemic profile, particularly overnight when variables are minimal. A consistent, well-adjusted system improves time-in-range and overall quality of life.
Ready for a Deeper Dive?
This episode is loaded with expert advice on optimizing your Omnipod Five settings—from basal programming to bolusing strategies and everything in between. Carrie Burgett and Scott Benner provide the essential information you need to set up your system for success and maintain a stable, responsive automated insulin delivery.
Don’t miss out on these crucial insights!
If you found these tips helpful, tune in to our full podcast episode—Omnipod Five Pro Tip Settings—available now on Juicebox Podcast. Listen to part two and explore the rest of our Omnipod Five series to fully empower your diabetes management journey.